In our recent question and answer, the pharmacist discusses whether or no there is one interaction in between NyQuil and also amoxicillin.

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Mary asked

Can ns take Amoxicillin and NyQuil in ~ the same time? İ have been acquisition amoxicillin for three days yet my symptoms obtained worse...started coughing every week and feel sick and also my chest feels heavy.


There space no drug interactions in between amoxicillin (Amoxil)and Nyquil (acetaminophen, dextromethorphan, and doxylamine). They have the right to safely be taken together. However, worseningsymptoms can be a authorize that the antibiotic is no working. It might benecessary to inspect with her physician around other treatment options. Below, wewill discuss an ext about the 2 medications.

Information on Amoxicillin

Amoxicillinis a beta-lactam antibiotic that is used for treatment of respiratory, sinus,and ear infections, among others. Due to the fact that amoxicillin is a kind of penicillin,it should not be take away in patient witha penicillin allergy. Reported allergies to penicillins are thought to behigher 보다 the price of true penicillin allergies. That is necessary to permit yourdoctor and also pharmacist recognize your allergies or various other adverse reaction beforetaking any kind of medication.

Amoxicillin is well absorbed in the GI tract and is metabolizedand eliminated primarily through the kidney. The is not generally metabolizedby CYP enzymes so will not influence metabolism of alcohol. Amoxicillin can causerash, nausea, vomiting, and also diarrhea.

In healthy patients, amoxicillin has a half-life around 1-2hours, definition the drug need to be fully cleared in ~ 12 hours. Inpatients with declined kidney function, the half-life might be significantlyincreased up to 13 hours (could take numerous days come be completely cleared).

Information on Nyquil

Nyquil come in avariety of formulations and contains several different ingredients. Nyquil Cold& Flu consists of the following:

Acetaminophen (pain relief, fever reducer)Dextromethorphan (cough suppressant)Doxylamine (antihistamine)

Acetaminophen is one analgesic that have the right to be taken because that a widevariety that acute and also chronic ache ailments. Acetaminophen has actually a half-life of2-3 hours. Acetaminophen gets took in at 85-98% and reaches peak concentrations in ~ 30-60 minutes.Typically, acetaminophen can startworking in ~ 15 minutes. Acetaminophen deserve to have an unfavorable impacts on theliver, specifically at greater doses because that an extended duration of time.

Dextromethorphan (commonly referred to as DM on manyover-the-counter products) is a coughsuppressant that reduce the advice to cough. That is finest to preventbothersome dry cough or a cough that doesn’t involve rubber from the lowerrespiratory system.

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Doxylamine is a first-generation antihistamine that is morelikely to cause sedation and also drowsinessas compared to second-generation antihistamines (i.e. Loratadine, cetirizine).Other first-generation antihistamines incorporate Benadryl (diphenhydramine),Dramamine (dimenhydrinate), Chlor-Trimeton (chlorpheniramine), Tavist(clemastine), and Phenergan (promethazine), among others.